Great for families, patients, academics, visitors and friends, given its spot in the, ahem, heart of Longwood Medical.

Coolly sophisticated design that's as sleek as it is comfortable.

Warehouse-chic design maximizes function in minimal space, and looks good doing it.

Ace location near the aquarium and, yes, the harbor.

Rooms rock a modern industrial-chic vibe with leather headboards and throwback phones.

Within walking distance of shops, eats and public transportation.

Waterfront setting along the Harborwalk, plus easy access to the North End's happenin' Hanover Street.

Vibrant spot in the heart of Boston's historic North End, overflowing with dining, shopping, and culture.

Invigoratingly modern with accents that reference Boston's long history.

Sweet boutique find perched atop North Station (with a terrace!), a 1-min jaunt to TD Garden.

Unique digs inspired by Boston’s spirit of innovation – with nods to athletes, artists and musicians who hail from this fair city.

Primping, preening and pampering to the max with onsite spa services.

Valet parking delivers all the fancy feels.

Hip Fort Point waterfront spot near all the happenin’ restaurants, plus museums and the convention center.

Innovation District address puts you within strolling distance of the World Trade Center, Institute of Contemporary Art & Financial District.

Free breakfast to keep hanger at bay.

Scenic setting right on Boston’s historic waterfront features stunning harbor and city views.

Rooms score big, with contemporary furniture earning style points and pillow-top beds snagging comfort points.

Plush old-school vibe is brimming with classic charm.

Exquisite and updated rooms feature bath and body products by Diptyque and an iPad on every table.

Snug in Boston's South End neighborhood, in the new and upscale Ink Block development.

Sophisticated modernism in the heart of the city, a short walking distance from the TD Garden. Go, Celtics!

Great for families, patients, academics, visitors and friends, given its spot in the, ahem, heart of Longwood Medical.

A classic, solid stay, with all the mod cons.

Central downtown location just across the street from TD Garden.

Free breakfast makes ya feel right at home (minus having to do the dishes!).

Well-placed for college visits, and bonus points for gym, pool and Charles River views.

Each chic, well-equipped suite boasts a kitchen(!) in case you're in the mood to get culinarily creative.

The onsite’s a no-brainer if you’re laying low for dinner. (Plus it gives you more time at the indoor pool.)

Enjoy Instagram-worthy views of the harbor and downtown skyline from this waterfront hotel.

Free shuttle to the train station makes it easy to zip into Boston without the hassle of parking.