Great for families, patients, academics, visitors and friends, given its spot in the, ahem, heart of Longwood Medical.

Rooms score big, with contemporary furniture earning style points and pillow-top beds snagging comfort points.

1886 home turned Back Bay boutique, complete with a cool cocktail lounge and patio.

Innovation District address puts you within strolling distance of the World Trade Center, Institute of Contemporary Art & Financial District.

Satisfy your burning urge for a bit of Americana – the homey former firehouse is decked out in it.

Coolly sophisticated design that's as sleek as it is comfortable.

Snug in Boston's South End neighborhood, in the new and upscale Ink Block development.

This AAA Four Diamond-rated hotel is pet-friendly (no fees!) and boasts a recently renovated lobby, onsite comedy club and free WiFi.

Invigoratingly modern with accents that reference Boston's long history.

Waterfront setting along the Harborwalk, plus easy access to the North End's happenin' Hanover Street.

Unique digs inspired by Boston’s spirit of innovation – with nods to athletes, artists and musicians who hail from this fair city.

Scenic setting right on Boston’s historic waterfront features stunning harbor and city views.

Sweet boutique find perched atop North Station (with a terrace!), a 1-min jaunt to TD Garden.

Warehouse-chic design maximizes function in minimal space, and looks good doing it.

Exquisite and updated rooms feature bath and body products by Diptyque and an iPad on every table.

Ace location near the aquarium and, yes, the harbor.

Sleep at the site of the Boston Tea Party – coffee's better anyway, right?

Plush old-school vibe is brimming with classic charm.

Gorgeous newly restored hotel steps from the public garden

Elegant sophistication in the heart of Beacon Hill. Steps from the Charles River, you're surrounded by bars and restaurants.

A classic, solid stay, with all the mod cons.

Sophisticated modernism in the heart of the city, a short walking distance from the TD Garden. Go, Celtics!

Great for families, patients, academics, visitors and friends, given its spot in the, ahem, heart of Longwood Medical.

Central downtown location just across the street from TD Garden.

Well-placed for college visits, and bonus points for gym, pool and Charles River views.

Machine- and Industrial-Age influences abound, plus modern touches like Smart TVs and free WiFi.

Free shuttle to the train station makes it easy to zip into Boston without the hassle of parking.

Well-equipped gym will please fitness fanatics, as will the gear & apparel rental program that lets ‘em pack light.

Pleasant stay 4 miles from Boston, with onsite dining, fitness room and li’l mini-mart for the inevitable forgotten something or other. Also: snacks.

Bring your furry friends along for the ride. This place is pet-friendly.

Just north of the city and not far from the airport.